Angel Di Maria, Julian Draxker and Edison Cavani were in target for Paris Saint-Germain as the hosts produced a mind-blowing performance to outplay Barcelona.
PSG dominated the match all over and took the lead through Di Maria’s curled free-kick, who was celebrating his 29th birthday.
Julian Draxler added a second with an angled drive before Di Maria curled another effort into the top corner.
Edinson Cavani then sealed a famous win with a powerful fourth.
The return leg will be played on 8 March at Camp Nou.