A Gonzalo Higuain brace at San Siro gave Juventus the 2-0 victory and plunged Milan back into crisis after poor Nikola Kalinic finishing.
Napoli found it perhaps tougher than expected, but pushed past Sassuolo 3-1 – including Jose Callejon from a corner – to stay as sole leaders.
Ciro Immobile contributed a goal and three assists, while Luis Nani got his first Serie A strike, as Lazio crushed Benevento 5-1.
A sensational Stephan El Shaarawy left-foot volley proved enough to give Roma the victory over a plucky Bologna side, their third straight 1-0 win.
RESULTS
AC Milan 0:2 Juventus
Roma 1:0 Bologna
Benevento 1:5 Lazio
Crotone 2:1 Fiorentina
Napoli 3:1 Sassuolo
Sampdoria 4:1 Chievo
SPAL 1:0 Genoa
Udinese 2:1 Atalanta
Torino 2:1 Cagliari